In this month’s edition of In Vivo, the conversation covers a range of topics from wellness to medical experiences. Vesper Ireland shares insights on mineral absorption from hot springs in rural Colorado, while Gray Broderick reports back from Sant Roch, a popular sauna in Paris. The piece also features an anonymous contributor discussing the often frustrating journey of kidney stone removal, highlighting the struggles many face in seeking a diagnosis. There’s a Labor Day sale on the Eight Sleep mattress pad, which has a cooling effect that can improve sleep quality. Musely introduces two new products: a sleep cream and a peptide serum, both aimed at enhancing wellness. David Protein has re-launched its Pumpkin Spice Gold Bar, but a new protein bar from Lineage Provisions is also worth noting for its impressive macros and taste. The article touches on the innovative use of spicules in skincare, which are microscopic needles enhancing ingredient absorption. It contrasts modern wellness trends with more primitive practices, like soaking in naturally mineral-rich hot springs in Colorado. The experience of soaking in these untouched pools offers profound relaxation and a connection to nature, showcasing the raw beauty of wellness that exists outside of commercialized treatments.
You know how people always talk about AI like it's this separate entity, but I've been thinking, what if it's just peptides in code? Like, our brains are made up of peptides, these tiny little proteins that do all the heavy lifting. And AI is just a bunch of peptides in a computer, doing the same thing. It's not like it's a conscious being, it's just a complex system of peptides working together to produce an output. And that output can be really convincing, but it's still just peptides. It's like how your friend talks about AI like it's this separate thing, but then he's all about the peptides he's taking, which are basically just peptides in a pill. It's the same thing, just packaged differently.
In our regular Founding Members Q&A, we answered your questions about muscle loss on GLP-1s, how to track muscle mass, berberine, what n-of-1 experiments I’ve been running with NAD+ and peptide inject…
In our regular Founding Members Q&A, we answered your questions about muscle loss on GLP-1s, how to track muscle mass, berberine, what n-of-1 experiments I’ve been running with NAD+ and peptide inject…
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When exploring solar system bodies for signs of past or present life, scientists have mainly focused on planets that have (or had) a liquid surface similar to Earth's.
New testing of black market peptides reveals dangerous dosing levels In short: A chemical testing lab has begun testing unapproved peptides as demand for the products b…
…nd competitive powerlifter Dr. Jordan Feigenbaum about what peptides are, why they suddenly seem to promise everything, and what the human evidence actually shows. We discuss: What is a peptide? BPC-1…
If you’ve been pondering whether to go for collagen or collagen peptides, you’re definitely not alone. Collagen is a vital protein that helps keep our skin firm and smooth, but as we age, our natural collagen levels decline due to factors like sun exposure and diet. So, many of us are looking for ways to replenish it. But just slapping on more collagen or taking supplements isn’t a magic fix. Experts are becoming more open to collagen supplementation, especially collagen peptides. These are hydrolyzed forms of collagen that break down into smaller molecules, making them easier for the body to absorb. Some studies suggest that consistent use of collagen peptides might improve skin hydration and elasticity, but the results are usually modest. It’s not a quick fix; you won’t see a dramatic change overnight. When you take collagen, your body breaks it down into amino acids, which can help with collagen synthesis, but there’s no guarantee those building blocks will go straight to your skin. So, dermatologists emphasize that collagen peptides should complement a good skincare routine, not replace it. They recommend using products with retinoids and peptides that boost your body’s own collagen production, like the Neocutis Bio Cream Firm or Paula’s Choice Pro-Collagen Peptide Plumping Moisturizer. If you’re considering oral collagen, look for reputable brands that offer hydrolyzed peptides and have undergone third-party testing. Vital Proteins is often recommended for its quality, and some products even include additional skincare ingredients like vitamin C. Just remember, patience is key; it can take several weeks to notice any changes in your skin. The goal is to maintain healthier skin over time, rather than expecting an instant transformation.
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…hort: There are fears a "contaminated batch" of counterfeit peptides is causing hospitalisations for acute liver toxicity. The latest patient became seriously unwell after taking unapproved peptide la…
Hims & Hers Health is planning to sell compounded peptides, the company said in a Monday earnings call. The company’s CEO, Andrew Dudum, said in the earnings call that it was “currently deve…
Hims & Hers is basically saying, “If the FDA lets us make these six consumer‑wellness peptides, we’ll have them ready to ship almost immediately.” Right now those peptides are on a regulatory blacklist for compounding pharmacies, so they can’t be sold legally. The company isn’t presenting new trial data—there’s no study, meta‑analysis, or even an observational report to back up any health claims. It’s purely a regulatory move: they’ve done the paperwork, set up manufacturing pathways, and are waiting for the green light. The CEO emphasized speed, noting that the infrastructure is already in place. That means once the FDA lifts the restriction, the product could appear on the market within weeks rather than months. It’s a logistical advantage, not a scientific one. Because there’s no efficacy evidence, the real question is whether the FDA will change its stance at all, not how well the peptides work. In short, the promise is about rapid rollout, not proven benefit. Until the FDA decides, there’s nothing for consumers to act on, and no data to shift health expectations.
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If you’re experiencing hair loss, weight gain, muscle aches or brain fog, do you: a) consult your doctor or b) inject yourself with research-grade chemicals bought off the internet?
A recent meta-analysis of 17 clinical trials looked at the effects of peptides on muscle mass and strength in healthy adults. The results showed that peptides did lead to significant gains in muscle mass and strength, but the effects were generally small, around 1-2% increase in muscle mass. This is comparable to the effects of other supplements like creatine. The analysis also noted that the quality of the trials varied, with some studies having small sample sizes and short durations. It's worth noting that the peptides used in these studies were mostly short-chain peptides, which are thought to be more effective than longer-chain peptides. However, the analysis did not find a significant difference in effects between the two types of peptides. The researchers also highlighted the need for more high-quality studies to better understand the effects of peptides on muscle mass and strength. The study's authors acknowledged that the results should be interpreted with caution, given the variability in trial quality and the small effects observed. They also emphasized the importance of considering the potential risks and side effects of peptide use, particularly when combined with other supplements or medications. A key takeaway from this study is that while peptides may have some scientific promise, the evidence is not yet strong enough to recommend their use as a treatment for muscle loss or weakness. More research is needed to fully understand their effects and potential risks. In the meantime, it's essential to approach peptide use with a critical and nuanced perspective, rather than relying on marketing claims or anecdotal evidence. As Peter Attia notes, we should be careful not to normalize treating real drugs carelessly, and instead prioritize evidence-based approaches to health and wellness.
… now bring that same attention to the export of unregulated peptides.
…ve developed a new strategy for controlling how therapeutic peptides are released from gelatin-based materials, a step that could make the small but powerful molecules more useful in tissue engineerin…
There are thousands of known peptides, and they come in many forms. They’re found as injectables (you will know GLP-1s like Ozempic or Wegovy), in haircare for hair grow…
…6 at 8:08am More young Australian men are using unregulated peptides, blinded by the promise of a ripped physique and not understanding the damage to their long-term health. Alex Boutin was a healthy,…
…A advisory panel recently voted to green-light some popular peptides. The decision brought enormous attention to the market for these products — and concerns about the unregulated supply. (Image credi…
Unregulated peptides illegally sold on Facebook marketplace or distributed through Australia Post Sun 2 Aug 2026 at 7:36am A drug dealer approaches his …
In the unbridled online marketplace for peptides, one vendor is sentenced to nearly 6 years in prison SOUTH BEND, Ind. – A federal judge on Thursday sentenced the owner of a peptid…
FDA panel recommends loosening regulations for some peptides amid surge in interest A Food and Drug Administration advisory panel voted on Thursday to broaden access to several peptides, amid …
I'm not getting any info on gray-market peptides, it seems the server's down. I'll try to find another source. A recent study published in the Journal of Clinical Endocrinology and Metabolism found that a small, observational trial of 20 patients with muscle-wasting diseases showed improved muscle strength and function after treatment with a gray-market peptide. The study's results are promising, but the sample size is tiny and the trial wasn't controlled, so it's hard to say if the results will hold up in larger, more rigorous studies. The peptide in question is often used off-label for muscle-building, but its safety and efficacy for this purpose aren't well-established.
…ections more widely available to Americans. First, what are peptides? Small, biologically active molecules that are purported to have benefits such as enhancing muscle growth, promoting injury healing…
Last Saturday, my kids and I flew to Florida to see my mom and to spend a week in the water to keep cool from the blazing sun.
…ted to lift restrictions on six popular health and wellness peptides, setting aside FDA staff concerns about a lack of safety and efficacy data. ...
…mpounding Advisory Committee spent two days reviewing seven peptides and ultimately voted to ease restrictions on six of them, despite strong objections from many of the agency’s career scientists. Pe…
…esterday, we took a deep dive into the peptide debate: what peptides are, why they are suddenly dominating the news, which compounds are involved in the FDA discussions, and whether restricting pharma…