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← Storyflo·Heather's IBS Newsletter - Help for Irritable Bowel Syndrome· health

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IBS news flash. Common IBS treatments linked to higher death risk

Heather Van Vorous, Author · Heather's IBS Newsletter - Help for Irritable Bowel Syndrome

Sep 29, 2026 · 1 min listen · Last updated September 29, 2026

A new large, long term study by Cedars-Sinai Health Sciences University of 650,000+ IBS patients over 20 years looked at the long-term safety of common IBS medications. There’s some bad news. Some commonly used treatments were linked to a higher risk of death over time.

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IBS news flash. Common IBS treatments linked to higher death risk

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A new large, long term study by Cedars-Sinai Health Sciences University of 650,000+ IBS patients over 20 years looked at the long-term safety of common IBS medications.

There’s some bad news.

Some commonly used treatments were linked to a higher risk of death over time.

Antidepressants were linked to a 35% higher risk of death.

The anti-diarrheal drugs loperamide and diphenoxylate were linked to roughly double the risk of death.

Some good news:

Other IBS medications, including the common antispasmodics, were not linked to any increased risk.

There is some important context:

The overall risk for any individual is still small

The study shows an

association, not proof that these drugs directly cause harmIncreased risk may be related to complications like heart issues, falls, or stroke

The study concluded that long-term use of some IBS medications may carry real risks, so treatments should be individualized and regularly reviewed with your doctor.

Don’t just rely on a medication indefinitely.

And learn more medications for IBS...

You are not alone.

P.S. If you need help or have questions hit the Green Button below and I’ll try to answer every one of you!

If you need immediate help please join my Private IBS Coaching.

XOXO

Heather

Heather Van Vorous

Over 40 years dealing with IBS

Get full help for IBS here

Get Heather’s Tummy Care here

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